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Increased myocardial fibrosis and impaired LV-contractility in a model of uremic cardiomyopathy leads to cardiac mTOR pathway activation with increased ER-stress, inflammation and apoptosis

Empagliflozin improves renal and cardiac function in heart failure irrespective of renal SGLT2 expression

Antibody based functional blocking of the ED-A domain of Fibronectin reduces expression of inflammatory genes in murine lungs in Sugen5416/Hypoxia induced pulmonary hypertension

Hypertension-related CRIP1 is affected by the renin-angiotensin-aldosterone system in the kidney

LPS induced exacerbation of Brugada syndrome with different gene variants

Functional investigation of a novel familial SCN5A mutation causative of Long QT syndrome.

The pathomechanism of a novel SLC4A3 variant in a family suffering from short-QT syndrome

Mechanisms of atrial-fibrillation-induced left ventricular dysfunction and recovery in human myocardium

Enhanced maturation of iPSC-CMs strongly improves their sensitivity to cardioactive drugs

Role of lipotoxicity in triggering electrophysiologic changes in induced pluripotent stem cell-derived cardiomyocytes from patients with arrhythmogenic right ventricular cardiomyopathy

Modelling and Drug Discovery of Clonal Hematopoiesis of Indeterminate Potential (CHIP)-driven Cardiovascular Disease in Self-organizing Cardiac Organoids (SCOs)

Growth differentiation factor 15 (GDF15) is elevated in human plaques, shuffles into the nucleus of ECs during EndMT, and promotes Endothelial-to-Mesenchymal Transition (EndMT)

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